Honest about the risks, and specific about what prevents each one.
Methanol-adulterated alcohol
The Government of Canada states that several foreigners in Vang Vieng have died or become severely ill from alcohol poisoning caused by suspected methanol-adulterated alcohol, and that Tiger brand vodka and whisky are prohibited and must not be bought or consumed. Methanol poisoning does not taste different and the symptoms can be delayed.
Prevention No free or extremely low-priced drinks. Buy only from licensed premises, in sealed containers you watch being opened. If you feel unwell after drinking, seek medical help immediately rather than sleeping it off.
Spiked and drugged food and drinks
The Government of Canada warns that some items sold to travellers — it names happy pizzas and special shakes — may contain unspecified amounts of opium and other unknown substances, and that foreigners, including Canadians, have died of drug overdoses. It also advises never leaving food or drink unattended. Separately, penalties for drug possession, use or trafficking are severe and may include the death penalty.
Prevention Do not order them. Do not accept food or drink from new acquaintances. Never carry a package for someone else.
Fresh water
CDC lists schistosomiasis, spread by wading, swimming, bathing or washing in contaminated fresh water; leptospirosis, from water or soil contaminated by infected animals; and melioidosis, from contaminated fresh water, mud or soil, especially after heavy rain. None has a vaccine.
Prevention Stay out of rivers, streams, ponds, lakes and untreated pools you cannot vouch for. Chlorinated pools and the sea are fine. Cover cuts and wash mud off promptly, particularly in the rainy season.
Dengue
Both sources name dengue as a risk to travellers in Laos, and the Government of Canada notes there is no vaccine or medication for it available in Canada. The mosquitoes that carry it bite during the day, so evening-only precautions miss them.
Prevention DEET 20%+ or picaridin through the day, reapplied. Screened or air-conditioned rooms, and a net where there is neither.
Roads
CDC notes motor vehicle crashes are the number one killer of healthy travellers abroad. The Government of Canada describes road conditions in Laos as poor, with insufficient lighting, unpaved roads, poorly maintained vehicles and stray livestock, and says drivers do not always respect traffic laws and can be aggressive and reckless.
Prevention Daylight travel on main roads. A proper helmet on any motorbike. Check your travel insurance actually covers motorbike accidents before you rent one.
Landmines and unexploded ordnance
The Government of Canada states that landmines and unexploded ordnance pose a risk throughout the country, and particularly at the Plain of Jars, in Xiengkhouang province and in the Lao–Vietnam border areas.
Prevention Stay on main roads and marked paths. Avoid walking in fields, rural areas and roadside ditches. Cross borders only at official crossings.
Rabies from dogs
The Government of Canada calls rabies common in Laos, carried by dogs and some wildlife including bats, and notes that treatment may be limited or not available. CDC states rabies-infected dogs are commonly found in the country.
Prevention Do not touch animals. Wash any bite or scratch with soap and water for 15 minutes and seek care immediately, vaccinated or not. Keep records of any treatment you receive abroad — the Government of Canada asks for that specifically.
Being evacuated
The Government of Canada describes medical facilities as scarce and below Canadian standards, with complex cases requiring medical evacuation to Thailand, and states that evacuation can be very expensive and difficult to organise.
Prevention Insurance that names medical evacuation and hospital stays. Policy number saved offline. Enough of your own medication for the whole trip, in labelled packaging.
Two regions the advisory singles out
Laos overall sits at "exercise a high degree of caution" with regional advisories. The Government of Canada advises avoiding non-essential travel to Xaisomboun province because of a tense security situation and random shooting incidents, and to the areas of Bokeo province within 10 km of the Myanmar and Thailand borders, including the Golden Triangle Special Economic Zone, because of criminal activity.
Prevention Check your route against the current advisory on travel.gc.ca before you book, not after. Levels change.
Avian influenza
The Government of Canada notes that human cases of avian influenza have been reported in Laos and advises avoiding contact with birds and making sure poultry is thoroughly cooked.
Prevention Stay out of live-poultry and wet markets. Cook poultry and eggs through. Wash hands after any animal contact.
Street crime
The Government of Canada says street crime is prevalent, with thieves on motorcycles grabbing bags and valuables, distraction thefts by pairs, break-ins at hotels and guesthouses, and occasional armed robberies and violent muggings in major cities.
Prevention Nothing medical here — carry bags on the wall side, keep passports secured, and avoid walking alone after dark.